TI-16 is a targeted peptide that selectively binds to β-amyloid (Aβ) protein and effectively crosses the blood-brain barrier. By increasing intracellular free calmodulin (CaM) concentration, TI-16 helps restore calcium ion homeostasis, thereby mitigating Aβ toxicity. This peptide has been demonstrated to reduce Aβ deposition in the brain, enhance neuronal health, inhibit cell apoptosis, and improve cognitive function in mouse models. TI-16 serves as a valuable reagent for research into Alzheimer's disease pathology and therapeutic strategies.
TI-16 is a targeted peptide that selectively binds to β-amyloid (Aβ) protein and effectively crosses the blood-brain barrier. By increasing intracellular free calmodulin (CaM) concentration, TI-16 helps restore calcium ion homeostasis, thereby mitigating Aβ toxicity. This peptide has been demonstrated to reduce Aβ deposition in the brain, enhance neuronal health, inhibit cell apoptosis, and improve cognitive function in mouse models. TI-16 serves as a valuable reagent for research into Alzheimer's disease pathology and therapeutic strategies.
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