Tyrosinase-IN-31 is a selective inhibitor of tyrosinase, targeting both monophenolase (IC50=70.44 μM) and diphenolase (IC50=1.89 μM) activities. This compound effectively inhibits tyrosinase and melanogenesis, demonstrating potential applications in skin depigmentation research. Additionally, Tyrosinase-IN-31 exhibits the ability to penetrate the blood-brain barrier, allowing it to enter the central nervous system, where it may confer neuroprotective effects and improve symptoms related to Parkinson's disease.
Tyrosinase-IN-31 is a selective inhibitor of tyrosinase, targeting both monophenolase (IC50=70.44 μM) and diphenolase (IC50=1.89 μM) activities. This compound effectively inhibits tyrosinase and melanogenesis, demonstrating potential applications in skin depigmentation research. Additionally, Tyrosinase-IN-31 exhibits the ability to penetrate the blood-brain barrier, allowing it to enter the central nervous system, where it may confer neuroprotective effects and improve symptoms related to Parkinson's disease.
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