Wikstrol B is a biflavonoid that acts as an inhibitor of microtubule polymerization and HIV-1 replication. It demonstrates an IC50 value of 184 μM for microtubule inhibition and an EC50 of 3.02 μM against HIV-1, affecting early replication processes. Additionally, Wikstrol B displays antifungal activity by inducing morphological changes in Pyricularia oryzae hyphae and exhibits anti-mitotic properties. This compound is valuable for research into antifungal, antitumor, and anti-HIV therapeutic applications. Naturally extracted from the roots of Wikstroemia indica, it offers a unique avenue for investigations in these domains.
Wikstrol B is a biflavonoid that acts as an inhibitor of microtubule polymerization and HIV-1 replication. It demonstrates an IC50 value of 184 μM for microtubule inhibition and an EC50 of 3.02 μM against HIV-1, affecting early replication processes. Additionally, Wikstrol B displays antifungal activity by inducing morphological changes in Pyricularia oryzae hyphae and exhibits anti-mitotic properties. This compound is valuable for research into antifungal, antitumor, and anti-HIV therapeutic applications. Naturally extracted from the roots of Wikstroemia indica, it offers a unique avenue for investigations in these domains.
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