YAP/TEAD-IN-2 is a potent inhibitor of the YAP/TEAD protein complex. It effectively reduces luciferase activity driven by YAP/TEAD in 293T cells, demonstrating its function as a reliable research tool. Additionally, YAP/TEAD-IN-2 exhibits significant anti-proliferative effects against human pleural mesothelioma NCI-H226 cells. This compound is relevant for research exploring diseases related to dysregulation of the Hippo signaling pathway, particularly in the context of various cancer types.
YAP/TEAD-IN-2 is a potent inhibitor of the YAP/TEAD protein complex. It effectively reduces luciferase activity driven by YAP/TEAD in 293T cells, demonstrating its function as a reliable research tool. Additionally, YAP/TEAD-IN-2 exhibits significant anti-proliferative effects against human pleural mesothelioma NCI-H226 cells. This compound is relevant for research exploring diseases related to dysregulation of the Hippo signaling pathway, particularly in the context of various cancer types.
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