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Z-DEVD-R110

Catalog No.: A25324
Fluorogenic Caspase-3/7 Substrate
Z-DEVD-R110 is a fluorogenic substrate specifically designed for the detection of caspase-3 and caspase-7 activity. Composed of two DEVD peptide sequences linked to the rhodamine 110 fluorophore, this reagent is valuable for studying apoptotic processes in various biological systems. Its ability to provide quantitative measurements of caspase activity makes it an essential tool in apoptosis research and related studies.
Z-DEVD-R110 223538-61-2 Fluorogenic Caspase-3/7 Substrate
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-DEVD-R110 is a fluorogenic substrate specifically designed for the detection of caspase-3 and caspase-7 activity. Composed of two DEVD peptide sequences linked to the rhodamine 110 fluorophore, this reagent is valuable for studying apoptotic processes in various biological systems. Its ability to provide quantitative measurements of caspase activity makes it an essential tool in apoptosis research and related studies.
Product Information
Catalog NumA25324
FormulaC72H78N10O27
Molecular Weight1515.44
CAS Number223538-61-2
Sequence{Z-Asp-Glu-Val-Asp}2-Rhodamine 110
Sequence shortening{Z-DEVD}2-Rhodamine 110
SMILESC([O-])(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC5=CC=CC=C5)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)=C4)C=C(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC6=CC=CC=C6)=O)CC(O)=O)=O)CCC(O)=O)=O)C(C)C)=O)CC(O)=O)=O)C=C3)C=CC=C1
Synonyms(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
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Apoptosis > Caspase
Proteases > Caspase