Zonisamide-15N,d4 is a stable isotope-labeled derivative of Zonisamide, designed for advanced chemical research applications. This compound functions primarily as a potent inhibitor of carbonic anhydrases hCA II and hCA V, with inhibition constants of 35.2 nM and 20.6 nM, respectively. Zonisamide demonstrates neuroprotective properties by promoting anti-apoptotic pathways and enhancing manganese superoxide dismutase (MnSOD) levels. Additionally, it increases the expression of Hrd1, contributing to improved cardiac function in animal models. This reagent is suitable for studies involving seizure disorders, Parkinson's disease, and cardiac hypertrophy research.
Zonisamide-15N,d4 is a stable isotope-labeled derivative of Zonisamide, designed for advanced chemical research applications. This compound functions primarily as a potent inhibitor of carbonic anhydrases hCA II and hCA V, with inhibition constants of 35.2 nM and 20.6 nM, respectively. Zonisamide demonstrates neuroprotective properties by promoting anti-apoptotic pathways and enhancing manganese superoxide dismutase (MnSOD) levels. Additionally, it increases the expression of Hrd1, contributing to improved cardiac function in animal models. This reagent is suitable for studies involving seizure disorders, Parkinson's disease, and cardiac hypertrophy research.
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