Arry-380 analog

Catalog No.: A11027
HER2 Inhibitor
ARRY-380 is an ErbB-2 inhibitor that selectively binds to and inhibits the phosphorylation of ErbB-2, resulting in growth inhibition and death of ErbB-2-expressing tumor cells.
Grouped product items
Product Name Price Stock Qty
Arry-380 5mg
$130.00
In stock
Arry-380 10mg
$221.00
In stock
Arry-380 50mg
$650.00
In stock
Arry-380 100mg
$1,100.00
In stock
Arry-380 10mM * 1mL in DMSO
$65.00
In stock
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Biological Activity
Discription ARRY-380 is an ErbB-2 inhibitor that selectively binds to and inhibits the phosphorylation of ErbB-2, resulting in growth inhibition and death of ErbB-2-expressing tumor cells.
Product Information
Catalog Num A11027
Formula C29H27N7O4S
Molecular Weight 569.9
CAS Number 937265-83-3
SMILES CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5
Synonyms Arry380
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 90 mg/mL (158 mM)
Water Insoluble
Ethanol 3 mg/mL (5.26 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.55 mL 87.73 mL 175.47 mL
0.5 mM 3.51 mL 17.55 mL 35.09 mL
1 mM 1.75 mL 8.77 mL 17.55 mL
5 mM 0.35 mL 1.75 mL 3.51 mL
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