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CDK inhibitor

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Catalog No. A11154

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BMS-265246 5mg A11154-5

Regular Price: $180.00

Special Price: $144.00

BMS-265246 10mg A11154-10

Regular Price: $300.00

Special Price: $240.00

BMS-265246 50mg A11154-50

Regular Price: $800.00

Special Price: $640.00

BMS-265246 100mg A11154-100

Regular Price: $1,400.00

Special Price: $1,120.00

BMS-265246 10mM * 1mL in DMSO A11154-10mM-D

Regular Price: $197.00

Special Price: $157.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BMS-265246 is a potent new pyra- zolopyridine inhibitor of cdk2/cyclin E and cdk1/cyclin B, as well as cdk4/cyclin D.


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Chemical Information

Catalog Num A11154
Actions Inhibitor
M. Wt 345.3
Formula C18H17F2N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 582315-72-8
Synonyms BMS265246
Chemical Name (4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone

Biological Activity

BMS-265246 is a potent new pyra- zolopyridine inhibitor of cdk2/cyclin E and cdk1/cyclin B, as well as cdk4/cyclin D.
CDK1/CyclinB (Cell-free assay) CDK2/CyclinE (Cell-free assay) CDK4/CyclinD (Cell-free assay)
6 nM9 nM230 nM


Solubility (25°C) * In vitro DMSO 20 mg/mL (57.91 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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