PHA-848125 (Milciclib)

Name: PHA-848125 (Milciclib)
SKU: A11047
Price: 40 USD
Rating: 5 (288 reviews)

Catalog No.: A11047

CDK Inhibitor

PHA-848125 (Milciclib) is an orally bioavailable inhibitor of CDKs and TRKA with potential antineoplastic activity.

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Grouped product items
Size	Price	Stock
1mg	$40.00	In stock
5mg	$95.00	In stock
10mg	$165.00	In stock
25mg	$390.00	In stock
50mg	$595.00	In stock
100mg	$915.00	In stock
200mg	$1,275.00	In stock
*10mM 1mL in DMSO**	$100.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription

PHA-848125 (Milciclib) is an orally bioavailable inhibitor of CDKs and TRKA with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A11047
Formula	C25H32N8O
Molecular Weight	460.6
CAS Number	802539-81-7
SMILES	CC1(CC2=CN=C(N=C2C3=C1C(=NN3C)C(=O)NC)NC4=CC=C(C=C4)N5CCN(CC5)C)C
Synonyms	Milciclib, PHA848125
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	91 mg/mL (197.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.71 mL	108.55 mL	217.11 mL
0.5 mM	4.34 mL	21.71 mL	43.42 mL
1 mM	2.17 mL	10.86 mL	21.71 mL
5 mM	0.43 mL	2.17 mL	4.34 mL

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