PHA-848125 (Milciclib)

Catalog No.: A11047
CDK Inhibitor
PHA-848125 (Milciclib) is an orally bioavailable inhibitor of CDKs and TRKA with potential antineoplastic activity.
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Product Name Stock
PHA-848125 5mg
PHA-848125 10mg
PHA-848125 50mg
PHA-848125 100mg
PHA-848125 (Milciclib) 10mM * 1mL in DMSO
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Biological Activity
Discription PHA-848125 (Milciclib) is an orally bioavailable inhibitor of CDKs and TRKA with potential antineoplastic activity.
Target Value
Product Information
Catalog Num A11047
Formula C25H32N8O
Molecular Weight 460.6
CAS Number 802539-81-7
Synonyms Milciclib, PHA848125

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 91 mg/mL (197.58 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.71 mL 108.55 mL 217.11 mL
0.5 mM 4.34 mL 21.71 mL 43.42 mL
1 mM 2.17 mL 10.86 mL 21.71 mL
5 mM 0.43 mL 2.17 mL 4.34 mL
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