KU-0063794

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mTOR Inhibitor

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Catalog No. A10505

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KU-0063794 5mg A10505-5

Regular Price: $50.00

Special Price: $42.50

KU-0063794 25mg A10505-25

Regular Price: $150.00

Special Price: $127.50

KU-0063794 50mg A10505-50

Regular Price: $220.00

Special Price: $187.00

KU-0063794 100mg A10505-100

Regular Price: $400.00

Special Price: $340.00

KU-0063794 10mM * 1mL in DMSO A10505-10mM-D

Regular Price: $50.00

Special Price: $42.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).

KU-0063794

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Chemical Information

Catalog Num A10505
Actions Inhibitor
M. Wt 465.5
Formula C25H31N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 938440-64-3
Synonyms KU0063794
SMILES code C[C@@H]1CN(C[C@@H](O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5
Chemical Name rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol

Biological Activity

Description
KU-0063794 is a selective inhibitor of mammalian target of rapamycin (mTOR) (IC50 ~10 nM for mTORC1 and mTORC2 respectively).
Targets
mTORC1 (Cell-free assay) mTORC2 (Cell-free assay)
~10 nM~10 nM

Solubility

Solubility (25°C) * In vitro DMSO 16 mg/mL (34.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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