19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue that exhibits low affinity for the vitamin D receptor (VDR) and minimal binding to the vitamin D binding protein (DBP). This compound effectively induces the differentiation of HL-60 cells and promotes G₀-G₁ phase cell cycle arrest. It serves as a valuable tool for investigating conditions such as excessive hyperparathyroidism in biological research.
19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue that exhibits low affinity for the vitamin D receptor (VDR) and minimal binding to the vitamin D binding protein (DBP). This compound effectively induces the differentiation of HL-60 cells and promotes G₀-G₁ phase cell cycle arrest. It serves as a valuable tool for investigating conditions such as excessive hyperparathyroidism in biological research.
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