TEI-9648 is a potent and specific antagonist of the vitamin D receptor (VDR). It effectively inhibits the genomic actions mediated by 1α,25(OH)2D3, blocking associated biological pathways. Additionally, TEI-9648 impedes the differentiation of HL-60 cells induced by 1α,25(OH)2D3. This compound demonstrates potential applications in research related to bone metabolism and VDR signaling pathways.
TEI-9648 is a potent and specific antagonist of the vitamin D receptor (VDR). It effectively inhibits the genomic actions mediated by 1α,25(OH)2D3, blocking associated biological pathways. Additionally, TEI-9648 impedes the differentiation of HL-60 cells induced by 1α,25(OH)2D3. This compound demonstrates potential applications in research related to bone metabolism and VDR signaling pathways.
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