Ro-65-2299 is an orally active vitamin D analogue that functions as a potential agonist of the vitamin D receptor (VDR), with an effective dose (ED50) of 180 nM. It promotes thickening of the epidermis and demonstrates antipsoriatic activity in hairless mice, with an ED50 of 7.5 mg/kg. This compound is suitable for research into inflammation and immunology, particularly in the context of psoriasis and related skin disorders.
Ro-65-2299 is an orally active vitamin D analogue that functions as a potential agonist of the vitamin D receptor (VDR), with an effective dose (ED50) of 180 nM. It promotes thickening of the epidermis and demonstrates antipsoriatic activity in hairless mice, with an ED50 of 7.5 mg/kg. This compound is suitable for research into inflammation and immunology, particularly in the context of psoriasis and related skin disorders.
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