(1R,5Z)-Calcitriol

Catalog No.: A85529
Calcitriol Isomer
(1R,5Z)-Calcitriol is an isomer of calcitriol, the most biologically active metabolite of vitamin D. This compound functions as a vitamin D receptor (VDR) agonist, influencing calcium metabolism and bone health. Its biological activity makes it valuable in research focused on bone disorders, immunomodulation, and calcium signaling pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(1R,5Z)-Calcitriol is an isomer of calcitriol, the most biologically active metabolite of vitamin D. This compound functions as a vitamin D receptor (VDR) agonist, influencing calcium metabolism and bone health. Its biological activity makes it valuable in research focused on bone disorders, immunomodulation, and calcium signaling pathways.
Product Information
Catalog NumA85529
FormulaC27H44O3
Molecular Weight416.64
CAS Number32511-63-0
SMILESC[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])/C(CCC1)=C/C=C3C(C(C[C@@H](C\3)O)O)=C
Synonyms(1R,5Z)-1,25-Dihydroxyvitamin D3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2