VDR agonist 2

Catalog No.: A85530
VDR Agonist
VDR Agonist 2 is a potent compound that acts as an agonist for the vitamin D receptor (VDR). This reagent effectively inhibits the TGF-β1-induced activation of hepatic stellate cells (HSC), demonstrating significant anti-hepatic fibrosis effects in both in vitro and in vivo studies. It is suitable for research applications focused on liver fibrosis and the mechanistic understanding of VDR-mediated pathways.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Biological Activity
DescriptionVDR Agonist 2 is a potent compound that acts as an agonist for the vitamin D receptor (VDR). This reagent effectively inhibits the TGF-β1-induced activation of hepatic stellate cells (HSC), demonstrating significant anti-hepatic fibrosis effects in both in vitro and in vivo studies. It is suitable for research applications focused on liver fibrosis and the mechanistic understanding of VDR-mediated pathways.
Product Information
Catalog NumA85530
FormulaC20H21F3O3
Molecular Weight366.37
CAS Number3052323-55-1
SMILESFC(F)(CCCOC1=CC=C(/C=C/C2=CC=C(C(CO)=C2)CO)C=C1)F
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