(1S)-Calcitriol is an active metabolite of 1α,25-dihydroxyvitamin D3, specifically targeting the vitamin D receptor (VDR). This compound exhibits significant biological activity, including the inhibition of keratinocyte proliferation and the suppression of parathyroid hormone secretion. Its VDR-mediated effects make (1S)-Calcitriol relevant for research in skin disorders, metabolic bone diseases, and the regulation of calcium homeostasis.
(1S)-Calcitriol is an active metabolite of 1α,25-dihydroxyvitamin D3, specifically targeting the vitamin D receptor (VDR). This compound exhibits significant biological activity, including the inhibition of keratinocyte proliferation and the suppression of parathyroid hormone secretion. Its VDR-mediated effects make (1S)-Calcitriol relevant for research in skin disorders, metabolic bone diseases, and the regulation of calcium homeostasis.
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