4-MU-α-GlcNS sodium is a fluorogenic substrate for heparin sulphamidase, which is desulfurized to produce 4-MU-α-GlcNH2. This metabolite is then hydrolyzed by α-glucosaminidase, resulting in the release of 4-methylumbelliferone (4-MU), a fluorescent compound with maximum emission wavelengths between 445-454 nm. 4-MU-α-GlcNS sodium is valuable in studying heparin sulphamidase deficiencies related to Mucopolysaccharidosis IIIA and other lysosomal disorders.
4-MU-α-GlcNS sodium is a fluorogenic substrate for heparin sulphamidase, which is desulfurized to produce 4-MU-α-GlcNH2. This metabolite is then hydrolyzed by α-glucosaminidase, resulting in the release of 4-methylumbelliferone (4-MU), a fluorescent compound with maximum emission wavelengths between 445-454 nm. 4-MU-α-GlcNS sodium is valuable in studying heparin sulphamidase deficiencies related to Mucopolysaccharidosis IIIA and other lysosomal disorders.
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