ACY-1215 (Rocilinostat)

Catalog No.: A11940
HDAC6 inhibitor
ACY-1215 selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation.
Grouped product items
Product Name Price Stock Qty
ACY-1215 10mg
$40.00
In stock
ACY-1215 50mg
$80.00
In stock
ACY-1215 100mg
$125.00
In stock
ACY-1215 (Rocilinostat) 10mM * 1mL in DMSO
$50.00
In stock
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Biological Activity
Discription ACY-1215 selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation.
Targets
Target Value
Product Information
Catalog Num A11940
Formula C24H27N5O3
Molecular Weight 433.5
CAS Number 1316214-52-4
SMILES C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO
Synonyms ACY1215
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 73 mg/mL (168.39 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.07 mL 115.34 mL 230.68 mL
0.5 mM 4.61 mL 23.07 mL 46.14 mL
1 mM 2.31 mL 11.53 mL 23.07 mL
5 mM 0.46 mL 2.31 mL 4.61 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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