HDAC10

Cat. No.

A10246

CAS No.

1012054-59-9

CUDC-101

CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.

Cat. No.

A11355

CAS No.

251456-60-7

M344

Synonyms: Histone Deacetylase Inhibitor III,MS344

M344 is a potent inhibitor of HDAC with IC50 of 100 nM and able to induce cell differentiation.

Cat. No.

A11940

CAS No.

1316214-52-4

ACY-1215 (Rocilinostat)

Synonyms: ACY1215

ACY-1215 selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation.

Cat. No.

A12911

CAS No.

1423058-85-8

BRD9757

BRD9757 is a highly potent and selective HDAC6 inhibitor with an IC50 of 30 nM toward HDAC6.

Cat. No.

A14032

CAS No.

1403783-31-2

Nexturastat A

Synonyms: Nexturastat-A,NexturastatA

Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM).

Cat. No.

A14341

CAS No.

1418033-25-6

LMK-235

LMK-235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor.

Cat. No.

A16770

CAS No.

1252003-15-8

Tubastatin A

Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).

Cat. No.

A21126

CAS No.

497833-27-9

Givinostat

Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.

Cat. No.

A12758

CAS No.

1316215-12-9

Citarinostat (ACY-241)

Synonyms: HDAC-IN-2; ACY-241

ACY-241 is a new, selective and orally available inhibitor of HDAC6.

Cat. No.

A10516

CAS No.

404951-53-7

Dacinostat (LAQ824, NVP-LAQ824)

Synonyms: LAQ824; NVP-LAQ824

LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.

Cat. No.

A10947

CAS No.

58880-19-6

Trichostatin A (TSA)

Synonyms: TSA

Trichostatin A (TSA) inhibits the HDACs 1, 3, 4, 6 and 10 with IC50 values around 20 nM.

Cat. No.

A10518

CAS No.

404950-80-7

Panobinostat (LBH589)

Synonyms: NVP-LBH589; LBH589

LBH589 is a hydroxamic acid and acts as a non-selective HDAC inhibitor with IC5o of HDAC1 to be 0.23 nM.

Cat. No.

A10700

CAS No.

783355-60-2

Abexinostat (PCI-24781)

Synonyms: CRA-024781; PCI-24781

PCI-24781 is a broad-spectrum phenyl hydroxamic acid HDAC inhibitor.

Cat. No.

A10492

CAS No.

875320-29-9

Quisinostat (JNJ-26481585)

Synonyms: JNJ-26481585

JNJ-26481585 (Quisinostat) is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).

Cat. No.

A10979

CAS No.

149647-78-9

Vorinostat (SAHA)

Synonyms: Zolinza; MK-0683; SAHA

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.