Antiviral agent 80

Catalog No.: A52057
Conjugate of Zanamivir-Amantadine
Antiviral agent 80 is a conjugate of Zanamivir and Amantadine, functioning as a dual inhibitor targeting the influenza virus M2 ion channel and neuraminidase (NA). This compound demonstrates potent inhibitory effects against both wild-type and drug-resistant influenza neuraminidase mutants, with an IC50 value range of 1.50 nM to 120.4 nM. Antiviral agent 80 is valuable for research applications focused on influenza pathogenesis and therapeutic strategies.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAntiviral agent 80 is a conjugate of Zanamivir and Amantadine, functioning as a dual inhibitor targeting the influenza virus M2 ion channel and neuraminidase (NA). This compound demonstrates potent inhibitory effects against both wild-type and drug-resistant influenza neuraminidase mutants, with an IC50 value range of 1.50 nM to 120.4 nM. Antiviral agent 80 is valuable for research applications focused on influenza pathogenesis and therapeutic strategies.
Product Information
Catalog NumA52057
FormulaC26H40N6O9
Molecular Weight580.63
CAS Number3110745-57-5
SMILESCC(N[C@H]1[C@H]([C@H](OC(NCCNC(C23CC4CC(C3)CC(C4)C2)=O)=O)[C@H](O)CO)OC(C(O)=O)=C[C@@H]1NC(N)=N)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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