Apyrase is a nucleoside triphosphate diphosphohydrolase (NTPDase) that hydrolyzes extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP). This enzymatic activity inhibits the release of Shiga toxin 2 (Stx2) from enterohemorrhagic Escherichia coli (EHEC), thereby providing protection to intestinal barrier function. Apyrase is a valuable tool for investigating mechanisms of infection and inflammation, particularly in studies related to hemorrhagic colitis.
Apyrase is a nucleoside triphosphate diphosphohydrolase (NTPDase) that hydrolyzes extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP). This enzymatic activity inhibits the release of Shiga toxin 2 (Stx2) from enterohemorrhagic Escherichia coli (EHEC), thereby providing protection to intestinal barrier function. Apyrase is a valuable tool for investigating mechanisms of infection and inflammation, particularly in studies related to hemorrhagic colitis.
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