AS-85

Name: AS-85
Brand: Adooq Bioscience
SKU: A26751
Rating: 5 (288 reviews)

Catalog No.: A26751

ASH1L Inhibitor

AS-85 is a potent inhibitor of the ASH1L histone methyltransferase, exhibiting an IC50 value of 0.6 μM. It demonstrates significant anti-leukemic activity through strong binding to the ASH1L SET domain, with a Kd value of 0.78 μM. This compound is useful in research focused on understanding the role of ASH1L in leukemia and other related disorders.

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Grouped product items
Size	Price	Stock
1mg	$110.00	In stock
5mg	$340.00	In stock
10mg	$580.00	In stock
25mg	$1,250.00	In stock
50mg	$1,950.00	In stock
100mg	$3,030.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	AS-85 is a potent inhibitor of the ASH1L histone methyltransferase, exhibiting an IC50 value of 0.6 μM. It demonstrates significant anti-leukemic activity through strong binding to the ASH1L SET domain, with a Kd value of 0.78 μM. This compound is useful in research focused on understanding the role of ASH1L in leukemia and other related disorders.

Product Information

Catalog Num	A26751
Formula	C26H28F3N5O3S2
Molecular Weight	579.66
CAS Number	2323623-80-7
SMILES	O=C(C1CNC1)NCC2=CC3=C(C=C2)C(C4=CC=CC(C(N)=S)=C4)=CN3C5CCN(S(=O)(C(F)(F)F)=O)CC5

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