PRMT5-IN-18

Catalog No.: A26686
PRMT5 Inhibitor
PRMT5-IN-18 is a highly effective inhibitor of protein arginine methyltransferase 5 (PRMT5), a key enzyme implicated in various cancer pathways. This compound demonstrates strong selectivity and potency, making it a valuable tool for investigating the role of PRMT5 in oncogenesis. Its utility in biochemical assays and cellular studies provides insights into potential therapeutic strategies targeting PRMT5-related diseases.
Grouped product items
Size Price Stock Qty
25mg
$1,800.00
In stock
50mg
$2,285.00
In stock
100mg
$2,815.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPRMT5-IN-18 is a highly effective inhibitor of protein arginine methyltransferase 5 (PRMT5), a key enzyme implicated in various cancer pathways. This compound demonstrates strong selectivity and potency, making it a valuable tool for investigating the role of PRMT5 in oncogenesis. Its utility in biochemical assays and cellular studies provides insights into potential therapeutic strategies targeting PRMT5-related diseases.
Product Information
Catalog NumA26686
FormulaC32H42N4O4
Molecular Weight546.70
CAS Number2756849-68-8
SMILESO=C1N(C[C@@H](O)[C@H]2NCC3=C(C=CC=C3)C2)CCN(CC)C4=CC(C(N(CC5)CCC65CC(OC)C6)=O)=CC=C14
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