β-AR antagonist 2 functions as a selective antagonist of β-adrenergic receptors, exhibiting an IC50 value of 0.17 μM. This compound has demonstrated significant inhibitory effects on the growth of mouse A549 xenograft tumors and exhibits cardioprotective properties in a model of doxorubicin-induced heart failure in C57 mice. Its applications in cancer research and cardiovascular studies make it a valuable tool for investigating β-AR signaling pathways.
β-AR antagonist 2 functions as a selective antagonist of β-adrenergic receptors, exhibiting an IC50 value of 0.17 μM. This compound has demonstrated significant inhibitory effects on the growth of mouse A549 xenograft tumors and exhibits cardioprotective properties in a model of doxorubicin-induced heart failure in C57 mice. Its applications in cancer research and cardiovascular studies make it a valuable tool for investigating β-AR signaling pathways.
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