BCM-599 is an endogenous metabolite that functions as a hepatitis B virus (HBV) capsid assembly inhibitor. It demonstrates potent antiviral activity with an IC50 value of 0.88 μM and a CC50 value of 144 μM in HepG2.2.15 cells. When administered in conjunction with lamivudine, BCM-599 exhibits a synergistic effect, enhancing the reduction of viral concentration. This compound is a valuable tool for investigating combined strategies for the treatment of HBV infection.
BCM-599 is an endogenous metabolite that functions as a hepatitis B virus (HBV) capsid assembly inhibitor. It demonstrates potent antiviral activity with an IC50 value of 0.88 μM and a CC50 value of 144 μM in HepG2.2.15 cells. When administered in conjunction with lamivudine, BCM-599 exhibits a synergistic effect, enhancing the reduction of viral concentration. This compound is a valuable tool for investigating combined strategies for the treatment of HBV infection.
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