Boceprevir-d9 is a deuterated form of Boceprevir, a selective and potent inhibitor of the HCV NS3 protease with a Ki value of 14 nM in enzyme assays. It demonstrates an EC90 of 350 nM in cell-based replicon assays, showcasing its efficacy against hepatitis C virus replication. Additionally, Boceprevir has been shown to inhibit SARS-CoV-2 3CLpro activity, making it valuable for research in antiviral drug development and therapeutic applications targeting viral proteases.
Boceprevir-d9 is a deuterated form of Boceprevir, a selective and potent inhibitor of the HCV NS3 protease with a Ki value of 14 nM in enzyme assays. It demonstrates an EC90 of 350 nM in cell-based replicon assays, showcasing its efficacy against hepatitis C virus replication. Additionally, Boceprevir has been shown to inhibit SARS-CoV-2 3CLpro activity, making it valuable for research in antiviral drug development and therapeutic applications targeting viral proteases.
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