BRD4 Inhibitor-28 is a selective inhibitor of the bromodomain protein BRD4, targeting the BRD4-BD1 and BRD4-BD2 domains with IC50 values of 15 nM and 55 nM, respectively. Additionally, it demonstrates inhibitory effects on BRD2-BD1, BRD3-BD1, and BRDT-BD1, with IC50 values of 19 nM, 25 nM, and 68 nM. This compound exhibits notable anti-melanoma activity, making it valuable for research in cancer therapeutics and epigenetic modulation.
BRD4 Inhibitor-28 is a selective inhibitor of the bromodomain protein BRD4, targeting the BRD4-BD1 and BRD4-BD2 domains with IC50 values of 15 nM and 55 nM, respectively. Additionally, it demonstrates inhibitory effects on BRD2-BD1, BRD3-BD1, and BRDT-BD1, with IC50 values of 19 nM, 25 nM, and 68 nM. This compound exhibits notable anti-melanoma activity, making it valuable for research in cancer therapeutics and epigenetic modulation.
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