- Cat. No.
- A10884
TAME
TAME is a small molecule anaphase-promoting complex/cyclosome (APC) inhibitor with an IC50 of 12 μM.
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- Cat. No.
- A21960
TAME hydrochloride
TAME hydrochloride is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest.
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- Cat. No.
- A22096
Apcin
Apcin, a ligand of Cdc20, is a potent and competitive anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity inhibitor.
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- Cat. No.
- A22207
Apcin-A
Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor.
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- Cat. No.
- A54063
proTAME
proTAME is a cell-permeable proagent that functions as an inhibitor of the anaphase promoting complex/cyclosome (APC/C). This compound effectively induces cell cycle arrest in the metaphase stage, making it a valuable tool for studying the regulation of mitosis and the role of APC/C in cell division. Its application extends to cancer research and investigations into cell cycle dynamics.
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- Cat. No.
- A54070
Apcin-A monohydrochloride
Apcin-A monohydrochloride is a selective inhibitor of the anaphase-promoting complex (APC) that effectively interacts with Cdc20, impeding the ubiquitination of its substrates. This compound is valuable for studying the regulatory mechanisms of protein degradation in mitosis and is applicable in research involving cell cycle regulation. Additionally, Apcin-A monohydrochloride can be utilized in the synthesis of the PROTAC CP5V, facilitating advanced studies in targeted protein degradation.
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