Coumarin-PEG2-TCO

Catalog No.: A45296
Fluorochrome Dye
Coumarin-PEG2-TCO is a fluorescent dye that features a coumarin backbone modified with two PEG units. It utilizes a trans-cyclooctene (TCO) group to engage in an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing compounds. This compound is valuable in biological imaging applications and has potential uses in the development of targeted fluorescent probes for live-cell imaging and other bioconjugation strategies.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCoumarin-PEG2-TCO is a fluorescent dye that features a coumarin backbone modified with two PEG units. It utilizes a trans-cyclooctene (TCO) group to engage in an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing compounds. This compound is valuable in biological imaging applications and has potential uses in the development of targeted fluorescent probes for live-cell imaging and other bioconjugation strategies.
Product Information
Catalog NumA45296
FormulaC29H41N3O7
Molecular Weight543.65
CAS Number2488174-19-0
SMILESO=C(O[C@H]1CCCCC/C=C\1)NCCOCCOCCNC(C2=CC3=CC=C(N(CC)CC)C=C3OC2=O)=O
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