Dasatinib-d4 is a deuterium-labeled derivative of Dasatinib, a potent ATP-competitive dual inhibitor targeting Src and Bcr-Abl. With IC50 values of less than 1.0 nM and 0.5 nM for Bcr-Abl and Src, respectively, Dasatinib effectively impedes tumor growth by inducing apoptosis and autophagy. This stable isotope-labeled compound is valuable for pharmacokinetic studies and metabolic investigations in cancer research, facilitating enhanced tracking of Dasatinib’s biological activity in various experimental settings.
Dasatinib-d4 is a deuterium-labeled derivative of Dasatinib, a potent ATP-competitive dual inhibitor targeting Src and Bcr-Abl. With IC50 values of less than 1.0 nM and 0.5 nM for Bcr-Abl and Src, respectively, Dasatinib effectively impedes tumor growth by inducing apoptosis and autophagy. This stable isotope-labeled compound is valuable for pharmacokinetic studies and metabolic investigations in cancer research, facilitating enhanced tracking of Dasatinib’s biological activity in various experimental settings.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
