Epigenetics

Part of Research Areas

Epigenetic regulation changes how genetic information is expressed without altering the underlying DNA sequence. These processes include covalent modification of DNA and histones, chromatin remodeling, and RNA-mediated control, and they shape cell identity, development, and responses to environmental signals. Disruption of epigenetic control is widely studied in cancer biology, inflammation, neurological research, and other areas of disease biology.

The category organizes research compounds around enzymes and binding proteins that write, erase, or interpret epigenetic marks. Major areas include HDACs and sirtuins, histone methyltransferases and demethylases, DNA methyltransferases and TET proteins, epigenetic reader domains, and regulators such as METTL3 and WDR5. Related categories covering PARP, microRNA, and protein methylation provide additional routes for investigating chromatin-associated and post-transcriptional regulation.

Explore Epigenetics

HDAC 495 Products PARP 252 Products JAK 338 Products Pim 62 Products Aurora Kinase 111 Products Sirtuins 151 Products Epigenetic Reader Domain 597 Products Histone Demethylases 170 Products DNA Methyltransferases 60 Products Histone Acetyltransferases 87 Products Histone Methyltransferase 424 Products Protein Arginine Methyltransferases 19 Products Protein Arginine Deiminase (PAD) 39 Products Methionine Adenosyltransferase (MAT) 38 Products MicroRNA 27 Products YTHDF 2 Products METTL3 26 Products WDR5 35 Products Human Antigen R (HuR) 9 Products TET Protein 7 Products FTO 16 Products OGT 12 Products SMARCA2/SMARCA4 (BRM/BRG1) 17 Products