Ferroptosis-IN-3 is a potent ferroptosis inhibitor targeting the ferroptotic cell death pathway. It effectively inhibits RSL3-induced ferroptosis in HT-1080 cells with an EC50 of 8.6 nM. Additionally, Ferroptosis-IN-3 demonstrates strong free radical scavenging properties, with EC50 values of 3.94 μM for DPPH and 6.3 μM for ABTS, and reduces lipid peroxidation. This compound is ideal for research focused on oxidative stress and cell death mechanisms.
Ferroptosis-IN-3 is a potent ferroptosis inhibitor targeting the ferroptotic cell death pathway. It effectively inhibits RSL3-induced ferroptosis in HT-1080 cells with an EC50 of 8.6 nM. Additionally, Ferroptosis-IN-3 demonstrates strong free radical scavenging properties, with EC50 values of 3.94 μM for DPPH and 6.3 μM for ABTS, and reduces lipid peroxidation. This compound is ideal for research focused on oxidative stress and cell death mechanisms.
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