HDAC8-IN-4 is a selective inhibitor of histone deacetylase 8 (HDAC8), demonstrating an IC50 of 0.15 μM for HDAC8 and 12 μM for HDAC3. This compound is crucial for studies focusing on epigenetic regulation and cancer biology, as it modulates histone acetylation and affects gene expression. HDAC8-IN-4 provides a valuable tool for exploring the therapeutic potential of HDAC inhibition in various diseases.
HDAC8-IN-4 is a selective inhibitor of histone deacetylase 8 (HDAC8), demonstrating an IC50 of 0.15 μM for HDAC8 and 12 μM for HDAC3. This compound is crucial for studies focusing on epigenetic regulation and cancer biology, as it modulates histone acetylation and affects gene expression. HDAC8-IN-4 provides a valuable tool for exploring the therapeutic potential of HDAC inhibition in various diseases.
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