JMV 236 is a potent histone methyltransferase inhibitor that modulates epigenetic regulation. It exhibits significant appetite-suppressing activity by antagonizing cholecystokinin, influencing the interaction between the intestinal peptide PrRP and the CCK1 receptor. This compound activates PrRP neurons in the nucleus of the solitary tract (NTS), enhancing its effects on food intake regulation, particularly in starvation conditions. JMV 236 is valuable in research applications focused on appetite control and metabolic disorders.
JMV 236 is a potent histone methyltransferase inhibitor that modulates epigenetic regulation. It exhibits significant appetite-suppressing activity by antagonizing cholecystokinin, influencing the interaction between the intestinal peptide PrRP and the CCK1 receptor. This compound activates PrRP neurons in the nucleus of the solitary tract (NTS), enhancing its effects on food intake regulation, particularly in starvation conditions. JMV 236 is valuable in research applications focused on appetite control and metabolic disorders.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
