- Wensheng Wang, .et al. Lymphatic endothelial cells produce M-CSF causing massive bone loss in mice, J Bone Miner Res, 2017, May; 32(5): 939-950 PMID: 28052488
Biological Activity
Ki 20227 is an inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.81 mL | 104.05 mL | 208.1 mL |
0.5 mM | 4.16 mL | 20.81 mL | 41.62 mL |
1 mM | 2.08 mL | 10.4 mL | 20.81 mL |
5 mM | 0.42 mL | 2.08 mL | 4.16 mL |
*The above data is based on the productmolecular weight 480.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11472 |
---|---|
Actions | Inhibitor |
M. Wt | 480.54 |
Formula | C24H24N4O5S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 623142-96-1 |
Synonyms | Ki-20227, Ki20227 |
SMILES | CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC |
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