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Ki 20227

Catalog No.: A11472

M-CSFR, CSF1R inhibitor

Ki 20227

Ki 20227 Chemical Structure

CAS NO. 623142-96-1

Ki 20227 is an inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R).

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Wensheng Wang, .et al. Lymphatic endothelial cells produce M-CSF causing massive bone loss in mice, J Bone Miner Res, 2017, May; 32(5): 939-950 PMID: 28052488

Biological Activity

Ki 20227 is an inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R).
In vitro DMSO 94 mg/mL (195.61 mM)
Water <1 mg/mL
Ethanol 3 mg/mL (6.24 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.81 mL 104.05 mL 208.1 mL
0.5 mM 4.16 mL 20.81 mL 41.62 mL
1 mM 2.08 mL 10.4 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11472
Actions Inhibitor
CAS No. 623142-96-1
Formula C24H24N4O5S
M. Wt 480.54
Purity >98%
Synonyms Ki-20227, Ki20227

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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