Tivozanib (AV-951)

Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors.
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Product Name Price Stock Qty
Tivozanib 5mg
Special Price $32.00 Regular Price $40.00
In stock
Tivozanib 10mg
Special Price $56.00 Regular Price $70.00
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Tivozanib 25mg
Special Price $96.00 Regular Price $120.00
In stock
Tivozanib 50mg
Special Price $144.00 Regular Price $180.00
In stock
Tivozanib (AV-951) 10mM * 1mL in DMSO
Special Price $76.00 Regular Price $95.00
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Adooq Products cited in reputable paper
Adooq's Tivozanib (AV-951) has been cited by 7 publications
  • Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932
  • Majid Momeny, .et al. , Life Sci, 2021, Dec 15;287:120100 PMID: 34715143
  • Majid Momeny, .et al. , Eur J Pharmacol, 2020, 882:173298
  • Majid Momeny, .et al. , Sci Rep, 2017, 7: 45954 PMID: 28383032
  • Majid Momeny, .et al. , Sci Rep, 2017, 7: 44075 PMID: 28287096
  • Nicholas A. Manieri, .et al. , J Clin Invest, 2015, Sep 1; 125(9): 3606-3618 PMID: 26280574
  • Usui T, .et al. , Acta Physiol (Oxf), 2014, 211, 385-394 PMID: 24612679
  • Biological Activity
    Discription Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors.
    Targets
    Target Value
    Product Information
    Catalog Num A10101
    Formula C22H19ClN4O5
    Molecular Weight 454.9
    CAS Number 475108-18-0
    SMILES CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 19 mg/mL (41.76 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.98 mL 109.91 mL 219.83 mL
    0.5 mM 4.4 mL 21.98 mL 43.97 mL
    1 mM 2.2 mL 10.99 mL 21.98 mL
    5 mM 0.44 mL 2.2 mL 4.4 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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