Tivozanib (AV-951)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors. | ||
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Targets |
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Catalog Num | A10101 |
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Formula | C22H19ClN4O5 |
Molecular Weight | 454.9 |
CAS Number | 475108-18-0 |
SMILES | CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 19 mg/mL (41.76 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.98 mL | 109.91 mL | 219.83 mL |
0.5 mM | 4.4 mL | 21.98 mL | 43.97 mL |
1 mM | 2.2 mL | 10.99 mL | 21.98 mL |
5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2