Fatty Acids & Derivatives

Cat. No.

A29252

CAS No.

1384526-74-2

Eicosapentaenoic acid (metformin)

Synonyms: EPA (metformin); Timnodonic acid (metformin)

Eicosapentaenoic Acid (EPA) functions as an omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA) with significant biological activity. It exhibits a DNA demethylating capability, facilitating the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Additionally, EPA activates the RAS/ERK/C/EBPβ signaling pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells, thereby enhancing cellular function. The compound also contributes to the relaxation of vascular smooth muscle cells and induces vasodilation, making it relevant for cardiovascular research.

Cat. No.

A29257

CAS No.

73167-03-0

Eicosapentaenoic Acid sodium

Synonyms: EPA sodium; Timnodonic acid sodium

Eicosapentaenoic Acid Sodium is an orally active omega-3 long-chain polyunsaturated fatty acid (LC-PUFA) that primarily targets DNA demethylation processes. This compound enhances the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ) and activates the RAS/ERK/C/EBPβ signaling pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Additionally, Eicosapentaenoic Acid Sodium is known to promote relaxation of vascular smooth muscle cells, contributing to vasodilation. This makes it a valuable reagent for studies in cancer biology and cardiovascular research.

Cat. No.

A49296

CAS No.

3032387-88-2

FASN-IN-6

FASN-IN-6 is a potent inhibitor of fatty acid biosynthesis (FAB). It demonstrates significant antibacterial activity, exhibiting minimum inhibitory concentrations (MIC) of 1 μg/mL against Staphylococcus aureus ATCC 25923 and 4 μg/mL against Enterococcus faecalis ATCC 29212. This compound is valuable for research applications focused on bacterial fatty acid biosynthesis and the development of novel antibacterial strategies.

Cat. No.

A49878

CAS No.

103904-74-1

Anacardic acid diene

Synonyms: Anacardic acid 15:2

Anacardic acid diene is a polyunsaturated fatty acid that targets various biological processes. It demonstrates significant antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus mutans, with minimum inhibitory concentrations (MICs) of 12.5 and 6.25 μg/mL, respectively. Additionally, Anacardic acid diene exhibits schistosomicidal properties against adult Schistosoma mansoni worms at a concentration of 100 μM and acts as a time-dependent inhibitor of soybean lipoxygenase-1. This compound is valuable for research into antibacterial agents, schistosomiasis treatment, and lipoxygenase inhibition.

Cat. No.

A59344

CAS No.

390824-20-1

UCM707

UCM707 is a potent and selective endocannabinoid uptake inhibitor. By inhibiting the reuptake of anandamide, it enhances its hypokinetic and antinociceptive effects, making it a valuable tool for studying the endocannabinoid system. This compound is useful in research applications related to pain management and the modulation of motor activity.

Cat. No.

A74664

CAS No.

1450603-63-0

FAAH inhibitor 2

FAAH Inhibitor 2 is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 of 0.153 μM. This compound is essential for studies evaluating endocannabinoid signaling pathways and the modulation of pain and inflammation. Its application in research aids in understanding the therapeutic potential of FAAH inhibition in various physiological and pathological states.

Cat. No.

A87628

CAS No.

98063-21-9

(R)-Aminocarnitine

Synonyms: Emeriamine

(R)-Aminocarnitine is an established inhibitor of fatty acid oxidation, demonstrating potential efficacy in reducing hyperglycemia and ketosis. This compound is valuable for research involving metabolic diseases, providing insights into metabolic dysregulation and potential therapeutic interventions. Its mechanism of action makes it a significant tool for studying the biochemical pathways involved in energy metabolism.

Cat. No.

A91195

CAS No.

162823-01-0

Sulfosuccinimidyl myristate sodium

Sulfosuccinimidyl myristate sodium is a potent inhibitor of fatty acid transport, specifically designed to obstruct the uptake of fatty acids in cellular models. By effectively inhibiting [14C]stearate uptake in isolated rat adipocytes, this reagent serves as a valuable tool for studying lipid metabolism and fatty acid signaling pathways in various biological contexts. Its utility extends to research involving obesity, metabolic disorders, and cell membrane dynamics.

Cat. No.

A96017

CAS No.

937738-63-1

Resolvin D1 methyl ester

Synonyms: RvD1 methyl ester

Resolvin D1 methyl ester is a potent inhibitor of triglyceride synthesis. This bioactive lipid mediates resolution of inflammation and has been shown to effectively lower triglyceride levels. It is commonly utilized in research applications focused on metabolic disorders and cardiovascular health.

Cat. No.

B20180

CAS No.

81741-99-3

Ro 22-0654

Ro 22-0654 is a potent inhibitor of lipid synthesis, targeting hepatic fatty acid production. It demonstrates significant antiobesity effects by disrupting lipid metabolism. This compound is valuable for research applications focused on metabolic disorders and obesity-related studies.