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Biological Activity
Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
| In vitro | DMSO | 67 mg/mL (179.18 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.74 mL | 133.72 mL | 267.44 mL |
| 0.5 mM | 5.35 mL | 26.74 mL | 53.49 mL |
| 1 mM | 2.67 mL | 13.37 mL | 26.74 mL |
| 5 mM | 0.53 mL | 2.67 mL | 5.35 mL |
*The above data is based on the productmolecular weight 373.921. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17333 |
|---|---|
| Actions | Agonist |
| CAS No. | 134-63-4 |
| Formula | C22H28ClNO2 |
| M. Wt | 373.921 |
| Purity | >98% |
| Synonyms | Lobeline hydrochloride |
| SMILES | CN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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