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Biological Activity
NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 7.14 mL | 35.69 mL | 71.37 mL |
| 0.5 mM | 1.43 mL | 7.14 mL | 14.27 mL |
| 1 mM | 0.71 mL | 3.57 mL | 7.14 mL |
| 5 mM | 0.14 mL | 0.71 mL | 1.43 mL |
*The above data is based on the productmolecular weight 1401.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11972 |
|---|---|
| Actions | Antagonist |
| CAS No. | 202983-32-2 |
| Formula | C49H30N6Na6O23S6 |
| M. Wt | 1401.1 |
| Purity | >98% |
| Synonyms | NF279, NF-279 |
| SMILES | C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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