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NF 279

P2X1 antagonist

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Catalog No. A11972

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NF 279 10mg A11972-10
NF 279 25mg A11972-25
NF 279 50mg A11972-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).

NF 279

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Chemical Information

Catalog Num A11972
Actions Antagonist
M. Wt 1401.1
Formula C49H30N6Na6O23S6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 202983-32-2
Synonyms NF279, NF-279
SMILES C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

Biological Activity

NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.14 mL 35.69 mL 71.37mL
0.5 mM 1.43 mL 7.14 mL 14.27 mL
1 mM 0.71 mL 3.57 mL 7.14 mL
5 mM 0.14 mL 0.71 mL 1.43 mL

*The above data is based on the productmolecular weight 1401.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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