NF 279

Catalog No.: A11972

P2X1 antagonist

NF 279

NF 279 Chemical Structure

CAS NO. 202983-32-2

NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).

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10 mg
$120.00
25 mg
$250.00
50 mg
$420.00
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Biological Activity

NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 μM in smooth muscle).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.14 mL 35.69 mL 71.37 mL
0.5 mM 1.43 mL 7.14 mL 14.27 mL
1 mM 0.71 mL 3.57 mL 7.14 mL
5 mM 0.14 mL 0.71 mL 1.43 mL

*The above data is based on the productmolecular weight 1401.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11972
Actions Antagonist
CAS No. 202983-32-2
Formula C49H30N6Na6O23S6
M. Wt 1401.1
Purity >98%
Synonyms NF279, NF-279
SMILES C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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