Nivocasan (GS-9450)

Catalog No.: A14100

Caspase inhibitor

Nivocasan (GS-9450)

Nivocasan (GS-9450) Chemical Structure

CAS NO. 908253-63-4

Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models.

Availability: Out of stock

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5 mg
$220.00
10 mg
$500.00
25 mg
$800.00
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Biological Activity

Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.36 mL 240.73 mL
0.5 mM 4.81 mL 24.07 mL 48.15 mL
1 mM 2.41 mL 12.04 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14100
Actions Inhibitor
CAS No. 908253-63-4
Formula C21H22FN3O5
M. Wt 415.41
Solubility DMSO
Purity >98%
Synonyms GS 9450,LB 84451 GS 9450,LB 84451
SMILES CC(C)[[email protected]]1(CC(=NO1)C2=CC=CC3=C2C=NC=C3)C(=O)N[[email protected]]4CC(=O)O[[email protected]@]4(CF)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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