NOD1/2 antagonist-2 is a dual antagonist of NOD1 and NOD2, exhibiting IC50 values of 2.36 μM and 4.16 μM, respectively. This compound effectively inhibits NF-κB and MAPK inflammatory signaling pathways, enhancing the efficacy of Paclitaxel in suppressing the growth of Lewis lung carcinoma. It is a valuable tool for investigating the roles of NOD1 and NOD2 in inflammation and cancer research.
NOD1/2 antagonist-2 is a dual antagonist of NOD1 and NOD2, exhibiting IC50 values of 2.36 μM and 4.16 μM, respectively. This compound effectively inhibits NF-κB and MAPK inflammatory signaling pathways, enhancing the efficacy of Paclitaxel in suppressing the growth of Lewis lung carcinoma. It is a valuable tool for investigating the roles of NOD1 and NOD2 in inflammation and cancer research.
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