ONC212

Catalog No.: A17056

ONC212

ONC212 Chemical Structure

CAS NO. 1807861-48-8

ONC212 is a fluorinated-ONC201 analogue, shows preclinical efficacy in melanoma and hepatocellular-cancer models. ONC212 is active in pancreatic cancer as single agent or in combination with 5-fluorouracil, irinotecan, oxaliplatin or RTK inhibitor crizotinib.

Availability: In stock

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5 mg

Regular Price: $110.00

Special Price $88.00

10 mg

Regular Price: $190.00

Special Price $152.00

50 mg

Regular Price: $720.00

Special Price $576.00

100 mg

Regular Price: $1,280.00

Special Price $1,024.00

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Biological Activity

ONC212 is a fluorinated-ONC201 analogue, shows preclinical efficacy in melanoma and hepatocellular-cancer models. ONC212 is active in pancreatic cancer as single agent or in combination with 5-fluorouracil, irinotecan, oxaliplatin or RTK inhibitor crizotinib.
In vitro DMSO 85 mg/mL (192.98 mM)
Water Insoluble
Ethanol 85 mg/mL (192.98 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.7 mL 113.52 mL 227.03 mL
0.5 mM 4.54 mL 22.7 mL 45.41 mL
1 mM 2.27 mL 11.35 mL 22.7 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17056
CAS No. 1807861-48-8
Formula C24H23F3N4O
M. Wt 440.47
Purity >98%
Synonyms ONC-212, ONC 212
SMILES O=C1N(CC2=CC=C(C(F)(F)F)C=C2)C3=NCCN3C4=C1CN(CC5=CC=CC=C5)CC4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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