Search by product name, CAS, target or catalog number. Press Down Arrow to reach product suggestions, Tab to move between links, and Escape to close suggestions.
Biochemical Assay Reagents collects small molecules used to prepare, run and calibrate biochemical and cell-based assays. Vitamins and cofactors such as niacin, riboflavin and biotin sit alongside sugars, sugar alcohols and amino acids such as L-arginine. Enzyme substrates and metal-ion chelators complete the range, including the calcium chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (BAPTA). Three subcategories group related reagents, namely Carbohydrates & Glycobiology, Acyl-CoA & Cofactors for acyl-coenzyme A (acyl-CoA) compounds, and Chelators & Bifunctional Chelators. Most of these compounds act as substrates, cofactors, standards or buffer components rather than as inhibitors of a defined target.
Synonyms: 1-Methoxy PMS; 1-Methoxyphenazine methosulfate
Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes.
Protamine from salmon is a biochemical assay reagent that serves as an antagonist to heparin, effectively neutralizing its anticoagulant effects. This compound exhibits antioxidant and antimicrobial properties, making it valuable in various research applications. It is particularly useful in studies involving antithrombin complexes, especially in canine samples pretreated with heparin in vitro.
Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium
NAD sodium is a crucial cofactor and homeostatic regulator that plays a significant role in cellular metabolism. It can be reduced to β-nicotinamide adenine dinucleotide (NADH) during oxidative reactions, facilitating ATP production within mitochondria. This compound is particularly relevant in research studying macrophage M2 polarization, non-alcoholic fatty liver disease, obesity, and glucose intolerance, making it a valuable reagent for investigations into metabolic syndrome and associated disorders.
Synonyms: Isopropyl β-D-thiogalactoside
IPTG (Isopropyl β-D-1-thiogalactopyranoside) acts as a molecular mimic of allolactose and serves as an inducer of the lac operon. This compound effectively triggers transcription in systems where gene expression is regulated by the lac operator, enabling controlled protein expression in biological research. IPTG is widely utilized in molecular biology and recombinant protein studies to regulate the activity of target genes within prokaryotic expression systems.
Thioglycolate sodium is an inflammation inducer that stimulates neutrophil and macrophage recruitment in vivo. This reagent is commonly utilized in research to induce peritonitis, allowing for the study of inflammatory responses and mechanisms in various biological contexts.
Synonyms: 1,2-Dimethylhydrazine dihydrochloride
N,N'-Dimethylhydrazine dihydrochloride is a potent tumor inducer targeting colon cancer pathways. This compound is widely used in rodent models to study the mechanisms of tumorigenesis and cancer progression. It serves as a valuable tool in cancer research, enabling the investigation of therapeutic approaches and the assessment of potential chemopreventive agents.
Benzyl piperazine-1-carboxylate is a synthetic intermediate primarily utilized in the development of melanocortin-4 (MC4) receptor antagonists. Its structural properties make it valuable in biochemical research aimed at understanding and modulating MC4 receptor activity, which is implicated in various physiological processes including appetite regulation and energy homeostasis. This compound serves as a critical building block for the synthesis of novel therapeutic candidates targeting the MC4 receptor.
Synonyms: 2-O-beta-D-Glucopyranosyl-D-glucopyranose monohydrate
Sophorose monohydrate is a disaccharide that acts as a biochemical assay reagent, primarily distinguished by its role in microbial glycolipids. This compound exhibits significant biological activities, including antibacterial, antifungal, spermicidal, virucidal, and anticancer properties. In research applications, sophorose monohydrate has been identified as a potent inducer of cellulase gene expression in Trichoderma reesei fermentation, making it valuable for studies focused on enzyme production and biosurfactant development.
Synonyms: β-D-1-thiogalactopyranoside hemidioxane
IPTG hemidioxane, also known as β-D-1-thiogalactopyranoside hemidioxane, serves as a potent biochemical reagent primarily utilized as an inducer of the lac operon in molecular biology research. It effectively promotes the expression of proteins in bacterial systems, enhancing the study of gene function and protein production. This reagent is essential for assays requiring controlled gene expression and is widely used in recombinant protein technology.
Out of stock
All 3 sizes
1,3-Dipropyl-7-methylxanthine is a selective antagonist of adenosine receptors, primarily targeting the A1 subtype. It exhibits potent inhibitory effects on adenosine-mediated signaling pathways, making it valuable in biochemical assays for studying adenosine receptor functions. This compound is commonly utilized in research examining cellular processes influenced by adenosine, such as neurotransmission, inflammation, and metabolic regulation.
Nestifylline is a biochemical reagent that functions primarily as an antagonist of adenosine receptors. It exhibits significant activity in modulating airway constriction, making it a valuable tool for studying respiratory diseases, particularly bronchospasm. Researchers can utilize Nestifylline to explore mechanisms underlying airway responsiveness and potential therapies for respiratory disorders.
Synonyms: 17-Phenyl trinor-13,14-dihydro PGA2
17-Phenyl trinor-13,14-dihydro prostaglandin A2 is a biochemical reagent that acts as a selective antagonist of prostaglandin receptors. It has been shown to modulate inflammatory responses and can be utilized in research to investigate the role of prostaglandins in various biological processes. This compound is valuable in studies related to cardiovascular health, reproductive biology, and cellular signaling pathways.
BMS-212122 is a biochemical assay reagent that functions as a selective antagonist of the p38 mitogen-activated protein kinase (MAPK). It exhibits significant inhibitory activity, making it a valuable tool for studying inflammation, cell signaling, and stress response pathways. This compound is widely utilized in life science research to explore therapeutic targets associated with various diseases, including autoimmune disorders and cancer.
Synonyms: Disulfide; bis(2,4-dimethylphenyl)
Dixylyl disulfide is a disulfide compound that functions as a chemical impurity reference standard in biochemical assays. Primarily utilized for monitoring impurities during the synthesis of hydrobromide vortioxetine, it aids in ensuring the purity of the final product. This hydrobromide derivative is known for its role as a 5-HT3, 5-HT7, and 5-HT1D receptor antagonist as well as a 5-HT1A receptor agonist, contributing to its antidepressant properties.
LH Secretion Antagonist 1 is a specific antagonist of luteinizing hormone secretion, functioning as a biochemical assay reagent. This compound is also recognized for its potential analgesic properties. Additionally, it features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it valuable for bioconjugation applications in chemical biology and drug discovery.
Out of stock
All 3 sizes