PAT-048

Catalog No.: A19187

Autotaxin inhibitor

PAT-048

PAT-048 Chemical Structure

CAS NO. 1359983-15-5

PAT-048 is a potent, selective and orally active autotaxin inhibitor, inhibits IL-6 mRNA expression, but shows no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in lung fibrosis model.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$2,000.00
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Biological Activity

PAT-048 is a potent, selective and orally active autotaxin inhibitor, inhibits IL-6 mRNA expression, but shows no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in lung fibrosis model.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.65 mL 108.25 mL 216.49 mL
0.5 mM 4.33 mL 21.65 mL 43.3 mL
1 mM 2.16 mL 10.82 mL 21.65 mL
5 mM 0.43 mL 2.16 mL 4.33 mL

*The above data is based on the productmolecular weight 461.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19187
Actions Inhibitor
CAS No. 1359983-15-5
Formula C22H18ClF2N3O2S
M. Wt 461.91
Purity >98%
Synonyms PAT048, PAT 048
SMILES CCCN1N=CC(N2C3=C(C(SC4=CC=CC(C(O)=O)=C4F)=C2C)C=CC(Cl)=C3F)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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