PF-06726304 acetate is a selective inhibitor of EZH2, a critical regulator of gene expression involved in epigenetic modifications. It effectively inhibits both wild-type and Y641N mutant forms of EZH2, exhibiting inhibition constants (Kis) of 0.7 nM and 3.0 nM, respectively. This compound demonstrates significant antitumor growth inhibition, making it a valuable tool for cancer research and therapeutic development targeting EZH2-related pathways.
PF-06726304 acetate is a selective inhibitor of EZH2, a critical regulator of gene expression involved in epigenetic modifications. It effectively inhibits both wild-type and Y641N mutant forms of EZH2, exhibiting inhibition constants (Kis) of 0.7 nM and 3.0 nM, respectively. This compound demonstrates significant antitumor growth inhibition, making it a valuable tool for cancer research and therapeutic development targeting EZH2-related pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
