PHA 408

Name: PHA 408
Brand: Adooq Bioscience
SKU: A13108
Rating: 5 (288 reviews)

Catalog No.: A13108

IKK-2 inhibitor

PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling.

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Grouped product items
Size	Price	Stock
1mg	$120.00	In stock
5mg	$320.00	In stock
10mg	$540.00	In stock
25mg	$980.00	In stock
50mg	$1,680.00	In stock
100mg	$2,495.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling.

Product Information

Catalog Num	A13108
Formula	C29H27ClFN7O2
Molecular Weight	560.02
CAS Number	503555-55-3
SMILES	CN1CCN(CC1)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl
Synonyms	PHA-408, PHA408
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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