(R)-Coriolic acid is an endogenous metabolite derived from the metabolism of linoleic acid through the action of lipoxygenase. It has been identified in the supernatants and membranes of cultured bovine endothelial cells, reflecting its role in COX-mediated pathways. Additionally, (R)-Coriolic acid is recognized as a weak inhibitor of U-46619-induced platelet aggregation, with an IC50 of 2.7 µM. This compound is valuable for research on lipid metabolism, cardiovascular function, and platelet biology.
(R)-Coriolic acid is an endogenous metabolite derived from the metabolism of linoleic acid through the action of lipoxygenase. It has been identified in the supernatants and membranes of cultured bovine endothelial cells, reflecting its role in COX-mediated pathways. Additionally, (R)-Coriolic acid is recognized as a weak inhibitor of U-46619-induced platelet aggregation, with an IC50 of 2.7 µM. This compound is valuable for research on lipid metabolism, cardiovascular function, and platelet biology.
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