Protein Tyrosine Kinases

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  1. VEGFR Antagonist

    Buflomedil is a vasoactive agent used to treat peripheral vascular disease.
  2. I3 receptor Antagonist

    KU14R is an antagonist of the pancreatic β-cell atypical imidazoline binding site (putative I3 receptor). KU14R has also been shown to selectively block efaroxan-induced insulin secretion.
  3. EGFR antagonist

    NRC-2694 is an epidermal growth factor receptor (EGFR) antagonist with anti-cancer and anti-proliferative properties.
  4. antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4

    BIO-013077-01, Novel potent antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4.

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