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SGC6870

Catalog No.: A26803
PRMT6 Allosteric Inhibitor
SGC6870 is a selective allosteric inhibitor of the protein arginine methyltransferase 6 (PRMT6), exhibiting an IC50 of 77 nM. This compound functions by modulating PRMT6 activity, thereby influencing cellular processes such as gene expression and signal transduction. SGC6870 is useful for research focused on epigenetic regulation and the role of PRMTs in various diseases, including cancer and neurodegenerative disorders.
SGC6870 2561471-27-8 PRMT6 Allosteric Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$155.00
In stock
5mg
$395.00
In stock
10mg
$755.00
In stock
25mg
$1,695.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSGC6870 is a selective allosteric inhibitor of the protein arginine methyltransferase 6 (PRMT6), exhibiting an IC50 of 77 nM. This compound functions by modulating PRMT6 activity, thereby influencing cellular processes such as gene expression and signal transduction. SGC6870 is useful for research focused on epigenetic regulation and the role of PRMTs in various diseases, including cancer and neurodegenerative disorders.
Product Information
Catalog NumA26803
FormulaC23H21BrN2O2S
Molecular Weight469.39
CAS Number2561471-27-8
SMILESO=C1CN(C(C2=CC=C(Br)S2)=O)[C@H](C3=CC(C)=CC(C)=C3)C4=CC(C)=CC=C4N1
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Epigenetics > Histone Methyltransferase