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SHLP-5

Catalog No.: B19217
Mitochondrial-Derived Peptide
SHLP-5 is a mitochondrial-derived peptide encoded by the 16s ribosomal RNA (MT-RNR2) gene, with a unique mechanism of action involving the modulation of various cellular processes. This biologically active microprotein exhibits potential neuroprotective, cardioprotective, and anti-inflammatory effects, making it valuable for research applications in diabetes, Alzheimer's disease, cardiovascular disorders, and prostate cancer. SHLP-5 serves as a critical tool for elucidating the role of mitochondrial peptides in health and disease.
SHLP-5 1191923-95-1 Mitochondrial-Derived Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSHLP-5 is a mitochondrial-derived peptide encoded by the 16s ribosomal RNA (MT-RNR2) gene, with a unique mechanism of action involving the modulation of various cellular processes. This biologically active microprotein exhibits potential neuroprotective, cardioprotective, and anti-inflammatory effects, making it valuable for research applications in diabetes, Alzheimer's disease, cardiovascular disorders, and prostate cancer. SHLP-5 serves as a critical tool for elucidating the role of mitochondrial peptides in health and disease.
Product Information
Catalog NumB19217
FormulaC114H173N25O36S3
Molecular Weight2565.93
CAS Number1191923-95-1
SequenceMet-Tyr-Cys-Ser-Glu-Val-Gly-Phe-Cys-Ser-Glu-Val-Ala-Pro-Thr-Glu-Ile-Phe-Asn-Ala-Gly-Leu-Val-Val
Sequence shorteningMYCSEVGFCSEVAPTEIFNAGLVV
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CCSC)N)=O)=O)CS)=O)CO)=O)CCC(O)=O)=O)C(C)C)=O)=O)=O)CS)=O)CO)=O)CCC(O)=O)=O)C(C)C)=O)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)C(C)C)=O)CC(C)C)=O)=O)C)=O)CC(N)=O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC3
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